Hippo pathway kinase Mst1 is required for long-lived humoral immunity

The protein kinase Mst1 is a key component of the evolutionarily conserved Hippo pathway that regulates cell survival, proliferation, differentiation, and migration. In humans, Mst1-deficiency causes primary immunodeficiency. Patients with MST1-null mutations show progressive loss of naïve T cells b...

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Udgivet i:J Immunol
Main Authors: Yazdchi, Sahar Bagherzadeh, Witalis, Mariko, Meli, Alexandre P., Leung, Joanne, Li, Xin, Panneton, Vincent, Chang, Jinsam, Li, Joanna, Nutt, Stephen L., Johnson, Randy L., Lim, Dae-Sik, Gu, Hua, King, Irah L., Suh, Woong-Kyung
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310088/
https://ncbi.nlm.nih.gov/pubmed/30478091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701407
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