Cargando...

H-ras inhibits the hippo pathway by promoting Mst1/Mst2 heterodimerization

The protein kinases Mst1 and Mst2 have tumor suppressor activity, but their mode of regulation is not well established. Mst1 and Mst2 are broadly expressed and may have certain overlapping functions in mammals, as deletions of both Mst1 and Mst2 together are required for tumorigenesis in mouse model...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Curr Biol
Main Authors: Rawat, Sonali J., Araiza-Olivera, Daniela, Arias-Romero, Luis E., Villamar-Cruz, Olga, Prudnikova, Tatiana Y., Roder, Heinrich, Chernoff, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915977/
https://ncbi.nlm.nih.gov/pubmed/27238285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.04.027
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!