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PI3K Gamma Inhibition Attenuates tPA-Induced Brain Hemorrhage and Improves Microvascular Patency After Embolic Stroke
Genetic and pharmacological inhibition of the phosphoinositide 3-kinase γ (PI3Kγ) exerts anti-inflammatory and protective effects in a number of inflammatory and autoimmune diseases. Spontaneously hypertensive rats subjected to embolic middle cerebral occlusion were treated with AS605240 (30 mg/kg)...
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| Publicado no: | Hypertension |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6309896/ https://ncbi.nlm.nih.gov/pubmed/30571560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12001 |
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