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High frequency of PTEN mutations in nevi and melanomas from xeroderma pigmentosum patients

We examined nevi and melanomas in 10 xeroderma pigmentosum (XP) patients with defective DNA repair. The lesions had a lentiginous appearance with markedly increased numbers of melanocytes. Using laser capture microdissection, we performed DNA sequencing of 18 benign and atypical nevi and 75 melanoma...

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Bibliografski detalji
Izdano u:Pigment Cell Melanoma Res
Glavni autori: Masaki, Taro, Wang, Yun, DiGiovanna, John J., Khan, Sikandar G., Raffeld, Mark, Beltaifa, Senda, Hornyak, Thomas J., Darling, Thomas N., Lee, Chyi-Chia R., Kraemer, Kenneth H.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309892/
https://ncbi.nlm.nih.gov/pubmed/24483290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12226
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