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High frequency of PTEN mutations in nevi and melanomas from xeroderma pigmentosum patients
We examined nevi and melanomas in 10 xeroderma pigmentosum (XP) patients with defective DNA repair. The lesions had a lentiginous appearance with markedly increased numbers of melanocytes. Using laser capture microdissection, we performed DNA sequencing of 18 benign and atypical nevi and 75 melanoma...
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| Publicado no: | Pigment Cell Melanoma Res |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6309892/ https://ncbi.nlm.nih.gov/pubmed/24483290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12226 |
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