High frequency of PTEN mutations in nevi and melanomas from xeroderma pigmentosum patients

We examined nevi and melanomas in 10 xeroderma pigmentosum (XP) patients with defective DNA repair. The lesions had a lentiginous appearance with markedly increased numbers of melanocytes. Using laser capture microdissection, we performed DNA sequencing of 18 benign and atypical nevi and 75 melanoma...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Pigment Cell Melanoma Res
Autori principali: Masaki, Taro, Wang, Yun, DiGiovanna, John J., Khan, Sikandar G., Raffeld, Mark, Beltaifa, Senda, Hornyak, Thomas J., Darling, Thomas N., Lee, Chyi-Chia R., Kraemer, Kenneth H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309892/
https://ncbi.nlm.nih.gov/pubmed/24483290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12226
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi