Phase I Trial and Pharmacokinetic Study of Sorafenib in Children With Neurofibromatosis Type I and Plexiform Neurofibromas

BACKGROUND. Sorafenib targets multiple pathways thought to be crucial in growth of plexiform neurofibroma (PN) in children with neurofibromatosis type 1 (NF1). Sorafenib has been tolerated with manageable toxicities in adults and children with refractory cancer. We conducted a separate study in this...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Pediatr Blood Cancer
Huvudupphovsmän: Kim, AeRang, Dombi, Eva, Tepas, Kathleen, Fox, Elizabeth, Martin, Staci, Wolters, Pamela, Balis, Frank M., Jayaprakash, Nalini, Turkbey, Baris, Muradyan, Naira, Choyke, Peter L., Reddy, Alyssa, Korf, Bruce, Widemann, Brigitte C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309697/
https://ncbi.nlm.nih.gov/pubmed/22961690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24281
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk