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Targeting mitochondrial dysfunction and oxidative stress in heart failure: challenges and opportunities

Mitochondrial dysfunction characterized by impaired bioenergetics, oxidative stress and aldehydic load is a hallmark of heart failure. Recently, different research groups have provided evidence that selective activation of mitochondrial detoxifying systems that counteract excessive accumulation of R...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Kiyuna, Ligia Akemi, Albuquerque, Rudá Prestes e, Chen, Che-Hong, Mochly-Rosen, Daria, Ferreira, Julio Cesar Batista
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309415/
https://ncbi.nlm.nih.gov/pubmed/30227272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2018.09.019
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