Urinary Extracellular Vesicle Protein Profiling and Endogenous Lithium Clearance Support Excessive Renal Sodium Wasting and Water Reabsorption in Thiazide-Induced Hyponatremia

INTRODUCTION: Thiazide diuretics are among the most widely used antihypertensive medications worldwide. Thiazide-induced hyponatremia (TIH) is 1 of their most clinically significant adverse effects. A priori TIH must result from excessive saliuresis and/or water reabsorption. We hypothesized that pa...

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Publicado en:Kidney Int Rep
Autores principales: Channavajjhala, Sarath K., Bramley, Roger, Peltz, Theresa, Oosthuyzen, Wilna, Jia, Wenjing, Kinnear, Sue, Sampson, Barry, Martin, Nick, Hall, Ian P., Bailey, Matthew A., Dear, James W., Glover, Mark
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
Materias:
Translational Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6308385/
https://ncbi.nlm.nih.gov/pubmed/30596177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ekir.2018.09.011
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