Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia

Thiazide diuretics are among the most widely used treatments for hypertension, but thiazide-induced hyponatremia (TIH), a clinically significant adverse effect, is poorly understood. Here, we have studied the phenotypic and genetic characteristics of patients hospitalized with TIH. In a cohort of 10...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Ware, James S., Wain, Louise V., Channavajjhala, Sarath K., Jackson, Victoria E., Edwards, Elizabeth, Lu, Run, Siew, Keith, Jia, Wenjing, Shrine, Nick, Kinnear, Sue, Jalland, Mahli, Henry, Amanda P., Clayton, Jenny, O’Shaughnessy, Kevin M., Tobin, Martin D., Schuster, Victor L., Cook, Stuart, Hall, Ian P., Glover, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669583/
https://ncbi.nlm.nih.gov/pubmed/28783044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI89812
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