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Evodiamine inhibits RANKL‐induced osteoclastogenesis and prevents ovariectomy‐induced bone loss in mice

Postmenopausal osteoporosis (PMO) is a progressive bone disease characterized by the over‐production and activation of osteoclasts in elderly women. In our study, we investigated the anti‐osteoclastogenic effect of evodiamine (EVO) in vivo and in vitro, as well as the underlying mechanism. By using...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Jin, Haiming, Yao, Lingya, Chen, Kai, Liu, Yuhao, Wang, Qingqing, Wang, Ziyi, Liu, Qian, Cao, Zhen, Kenny, Jacob, Tickner, Jennifer, Wang, Xiangyang, Xu, Jiake
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307789/
https://ncbi.nlm.nih.gov/pubmed/30451360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13955
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