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Overexpression of PDK4 is associated with cell proliferation, drug resistance and poor prognosis in ovarian cancer

PURPOSE: Ovarian cancer is a major type of gynecological malignancy which characterized by the chemoresistance, heterogeneity and highly metastasis. However, the mechanism underlying the progression of ovarian cancer remains elusive. Pyruvate dehydrogenase kinase family plays critical roles in tumor...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Wang, Jinghao, Qian, Yu, Gao, Meiyan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307676/
https://ncbi.nlm.nih.gov/pubmed/30636897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S185015
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