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Thrombin contributes to the injury development and neurological deficit after acute subdural hemorrhage in rats only in collaboration with additional blood-derived factors

BACKGROUND: Acute subdural hemorrhage (ASDH) is a severe consequence of traumatic brain injury. The occurrence of subdural blood increases the lethality of these patients independent of the amount of blood or elevated intracranial pressure. Thrombin is one of the potential harmful blood components....

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Publicado en:BMC Neurosci
Main Authors: Krämer, Tobias J., Sakas, Wasim, Jussen, Daniel, Krenzlin, Harald, Kempski, Oliver, Alessandri, Beat
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307215/
https://ncbi.nlm.nih.gov/pubmed/30591020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-018-0481-5
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