High CSF thrombin concentration and activity is associated with an unfavorable outcome in patients with intracerebral hemorrhage

BACKGROUND: The cerebral thrombin system is activated in the early stage after intracerebral hemorrhage (ICH). Expression of thrombin leads to concentration dependent secondary neuronal damage and detrimental neurological outcome. In this study we aimed to investigate the impact of thrombin concentr...

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Foilsithe in:PLoS One
Main Authors: Krenzlin, Harald, Frenz, Christina, Schmitt, Jan, Masomi-Bornwasser, Julia, Wesp, Dominik, Kalasauskas, Darius, Kerz, Thomas, Lotz, Johannes, Alessandri, Beat, Ringel, Florian, Keric, Naureen
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2020
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657554/
https://ncbi.nlm.nih.gov/pubmed/33175864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241565
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