High CSF thrombin concentration and activity is associated with an unfavorable outcome in patients with intracerebral hemorrhage

BACKGROUND: The cerebral thrombin system is activated in the early stage after intracerebral hemorrhage (ICH). Expression of thrombin leads to concentration dependent secondary neuronal damage and detrimental neurological outcome. In this study we aimed to investigate the impact of thrombin concentr...

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Vydáno v:PLoS One
Hlavní autoři: Krenzlin, Harald, Frenz, Christina, Schmitt, Jan, Masomi-Bornwasser, Julia, Wesp, Dominik, Kalasauskas, Darius, Kerz, Thomas, Lotz, Johannes, Alessandri, Beat, Ringel, Florian, Keric, Naureen
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657554/
https://ncbi.nlm.nih.gov/pubmed/33175864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241565
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