Salidroside improves the hypoxic tumor microenvironment and reverses the drug resistance of platinum drugs via HIF-1α signaling pathway

BACKGROUND: Hypoxia commonly occurs in solid tumors. The hypoxia in the center of solid tumors considerably decreases the chemosensitivity of tumor cells and induces epithelial–mesenchymal transition (EMT) as well as drug resistance of antitumor drugs. METHODS: Here, the effects of salidroside (Sal)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EBioMedicine
Egile Nagusiak: Qin, Yuan, Liu, Hui-juan, Li, Meng, Zhai, Deng-hui, Tang, Yuan-hao, Yang, Lan, Qiao, Kai-liang, Yang, Jia-huan, Zhong, Wei-long, Zhang, Qiang, Liu, Yan-rong, Yang, Guang, Sun, Tao, Yang, Cheng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2018
Gaiak:
Research paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306459/
https://ncbi.nlm.nih.gov/pubmed/30396856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.10.069
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