Myofibroblasts in macular fibrosis secondary to neovascular age-related macular degeneration - the potential sources and molecular cues for their recruitment and activation

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly in developed countries. Neovascular AMD (nAMD) accounts for 90% of AMD-related vision loss. Although intravitreal injection of VEGF inhibitors can improve vision in nAMD, approximately 1/3 of patients do not bene...

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Enregistré dans:
Détails bibliographiques
Publié dans:EBioMedicine
Auteurs principaux: Little, Karis, Ma, Jacey H., Yang, Nan, Chen, Mei, Xu, Heping
Format: Artigo
Langue:Inglês
Publié: Elsevier 2018
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306402/
https://ncbi.nlm.nih.gov/pubmed/30473378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.11.029
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