P38 MAPK inhibition prevents polybrene-induced senescence of human mesenchymal stem cells during viral transduction

The unique capacity of mesenchymal stem cells (MSCs) to migrate to the sites of damage, following intravenous transplantation, along with their proliferation and differentiation abilities make them promising candidates for MSC-based gene therapy. This therapeutic approach requires high efficacy deli...

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Veröffentlicht in:PLoS One
Hauptverfasser: Griukova, Anastasiia, Deryabin, Pavel, Sirotkina, Maria, Shatrova, Alla, Nikolsky, Nikolay, Borodkina, Aleksandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306270/
https://ncbi.nlm.nih.gov/pubmed/30586456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209606
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