Anti-Mucin1 Aptamer-Conjugated Chitosan Nanoparticles for Targeted Co-Delivery of Docetaxel and IGF-1R siRNA to SKBR3 Metastatic Breast Cancer Cells

BACKGROUND: Targeted co-delivery of siRNA and a chemotherapeutic drug is an attractive approach to cancer drug design and treatment. This study was carried out to design an anti-Mucin1 aptamer (Apt)-conjugated chitosan nanoparticle (NP) for targeted co-delivery of insulin-like growth factor receptor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Iran Biomed J
Prif Awduron: Jafari, Reza, Zolbanin, Naime Majidi, Majidi, Jafar, Atyabi, Fatemeh, Yousefi, Mehdi, Jadidi-Niaragh, Farhad, Aghebati-Maleki, Leili, Shanehbandi, Dariush, Zangbar, Mohammad-Sadegh Soltani, Rafatpanah, Houshang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Pasteur Institute 2019
Pynciau:
Full Length
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305820/
https://ncbi.nlm.nih.gov/pubmed/30041514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29252/.23.1.21
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