Developing and characterization of single chain variable fragment (scFv) antibody against frizzled 7 (Fzd7) receptor

Wnt/β-catenin signaling pathway through Frizzled receptors has been shown to play a key role in both normal development and tumorigenesis. Overexpression of Wnt pathway genes, such as Fzd7 in several malignancies is well-documented. Therefore, targeting of Fzd7 and its ligand inhibits cancer cells p...

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Publicado en:Bioengineered
Autores principales: Nickho, Hamid, Younesi, Vahid, Aghebati-Maleki, Leili, Motallebnezhad, Morteza, Majidi Zolbanin, Jafar, Movassagh Pour, Aliakbar, Yousefi, Mehdi
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639855/
https://ncbi.nlm.nih.gov/pubmed/27849134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2016.1255383
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