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Whole exome sequencing for the identification of CYP3A7 variants associated with tacrolimus concentrations in kidney transplant patients
The purpose of this study was to identify genotypes associated with dose-adjusted tacrolimus trough concentrations (C(0)/D) in kidney transplant recipients using whole-exome sequencing (WES). This study included 147 patients administered tacrolimus, including seventy-five patients in the discovery s...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6305386/ https://ncbi.nlm.nih.gov/pubmed/30584253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36085-w |
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