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Epigenetic changes around the pX region and spontaneous HTLV-1 transcription are CTCF-independent

Background: The human retrovirus HTLV-1 inserts the viral complementary DNA of 9 kb into the host genome. Both plus- and minus-strands of the provirus are transcribed, respectively from the 5′ and 3′ long terminal repeats (LTR). Plus-strand expression is rapid and intense once activated, whereas the...

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Bibliografische gegevens
Gepubliceerd in:Wellcome Open Res
Hoofdauteurs: Miura, Michi, Miyazato, Paola, Satou, Yorifumi, Tanaka, Yuetsu, Bangham, Charles R.M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: F1000 Research Limited 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305241/
https://ncbi.nlm.nih.gov/pubmed/30607369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.14741.2
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