The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome

Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that causes malignant and inflammatory diseases in ∼10% of infected people. A typical host has between 10(4) and 10(5) clones of HTLV-1–infected T lymphocytes, each clone distinguished by the genomic integration site of the single-copy HTLV-...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Satou, Yorifumi, Miyazato, Paola, Ishihara, Ko, Yaguchi, Hiroko, Melamed, Anat, Miura, Michi, Fukuda, Asami, Nosaka, Kisato, Watanabe, Takehisa, Rowan, Aileen G., Nakao, Mitsuyoshi, Bangham, Charles R. M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801255/
https://ncbi.nlm.nih.gov/pubmed/26929370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423199113
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