Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB

Hyperphosphorylated α-synuclein in Lewy bodies and Lewy neurites is a characteristic neuropathological feature of Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB). The catalytic subunit of the specific phosphatase, protein phosphatase 2A (PP2A) that dephosphorylates α-synuclein, is hypom...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yan, Run, Zhang, Jie, Park, Hye-Jin, Park, Eun S., Oh, Stephanie, Zheng, Haiyan, Junn, Eunsung, Voronkov, Michael, Stock, Jeffry B., Mouradian, M. Maral
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304960/
https://ncbi.nlm.nih.gov/pubmed/30509990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813365115
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados