Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity

TNF is a multifunctional cytokine involved in autoimmune disease pathogenesis that exerts its effects through two distinct TNF receptors, TNFR1 and TNFR2. While TNF- and TNFR1-deficient (but not TNFR2-deficient) mice show very similar phenotypes, the significance of TNFR2 signaling in health and dis...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Atretkhany, Kamar-Sulu N., Mufazalov, Ilgiz A., Dunst, Josefine, Kuchmiy, Anna, Gogoleva, Violetta S., Andruszewski, David, Drutskaya, Marina S., Faustman, Denise L., Schwabenland, Marius, Prinz, Marco, Kruglov, Andrey A., Waisman, Ari, Nedospasov, Sergei A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304938/
https://ncbi.nlm.nih.gov/pubmed/30498033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807499115
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