Proximity Ligation Assays for In Situ Detection of Innate Immune Activation: Focus on In Vitro-Transcribed mRNA

The characterization of innate immune activation is crucial for vaccine and therapeutic development, including RNA-based vaccines, a promising approach. Current measurement methods quantify type I interferon and inflammatory cytokine production, but they do not allow for the isolation of individual...

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Publicat a:Mol Ther Nucleic Acids
Autors principals: Blanchard, Emmeline L., Loomis, Kristin H., Bhosle, Sushma M., Vanover, Daryll, Baumhof, Patrick, Pitard, Bruno, Zurla, Chiara, Santangelo, Philip J.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304375/
https://ncbi.nlm.nih.gov/pubmed/30579042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.11.002
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