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The interactions of novel mononuclear platinum-based complexes with DNA
BACKGROUND: Cisplatin has been widely used for the treatment of cancer and its antitumour activity is attributed to its capacity to form DNA adducts, predominantly at guanine residues, which impede cellular processes such as DNA replication and transcription. However, there are associated toxicity a...
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| Publicado en: | BMC Cancer |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6303901/ https://ncbi.nlm.nih.gov/pubmed/30577821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5194-8 |
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