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Cardiac effects of 6 months' dietary nitrate and spironolactone in patients with hypertension and with/at risk of type 2 diabetes, in the factorial design, double‐blind, randomized controlled VaSera trial

AIMS: The aims of the present study were to explore whether a long‐term intervention with dietary nitrate [(NO(3) (−)), a potential tolerance‐free source of beneficial vasoactive nitric oxide] and spironolactone (to oppose aldosterone's potential deleterious cardiovascular effects) improve card...

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Foilsithe in:Br J Clin Pharmacol
Main Authors: Faconti, Luca, Mills, Charlotte Elizabeth, Govoni, Virginia, Gu, Haotian, Morant, Steven, Jiang, Benju, Cruickshank, J. Kennedy, Webb, Andrew James
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303216/
https://ncbi.nlm.nih.gov/pubmed/30294825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13783
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