Predicting tumor cell line response to drug pairs with deep learning

BACKGROUND: The National Cancer Institute drug pair screening effort against 60 well-characterized human tumor cell lines (NCI-60) presents an unprecedented resource for modeling combinational drug activity. RESULTS: We present a computational model for predicting cell line response to a subset of d...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Xia, Fangfang, Shukla, Maulik, Brettin, Thomas, Garcia-Cardona, Cristina, Cohn, Judith, Allen, Jonathan E., Maslov, Sergei, Holbeck, Susan L., Doroshow, James H., Evrard, Yvonne A., Stahlberg, Eric A., Stevens, Rick L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302446/
https://ncbi.nlm.nih.gov/pubmed/30577754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2509-3
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