Endogenous cholesterol ester hydroperoxides modulate cholesterol levels and inhibit cholesterol uptake in hepatocytes and macrophages

Dysregulation of cholesterol metabolism represents one of the major risk factors for atherosclerotic cardiovascular disease (CVD). Oxidized cholesterol esters (oxCE) in low-density lipoprotein (LDL) have been implicated in CVD but the underlying mechanisms remain poorly defined. We use a targeted li...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Guo, Shuyuan, Lu, Jianhong, Zhuo, Yujuan, Xiao, Mengqing, Xue, Xinli, Zhong, Shanshan, Shen, Xia, Yin, Chunzhao, Li, Luxiao, Chen, Qun, Zhu, Mingjiang, Chen, Buxing, Zhao, Mingming, Zheng, Lemin, Tao, Yongzhen, Yin, Huiyong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302155/
https://ncbi.nlm.nih.gov/pubmed/30576926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.101069
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