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CRISPR/Cas9 Genome Editing to Disable the Latent HIV-1 Provirus
HIV-1 infection can be successfully controlled with anti-retroviral therapy (ART), but is not cured. A reservoir of cells harboring transcriptionally silent integrated provirus is able to reestablish replicating infection if ART is stopped. Latently HIV-1 infected cells are rare, but may persist for...
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| Publicado no: | Front Microbiol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6302043/ https://ncbi.nlm.nih.gov/pubmed/30619186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.03107 |
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