Inhibiting crosstalk between MET signaling and mitochondrial dynamics and morphology: a novel therapeutic approach for lung cancer and mesothelioma

The receptor tyrosine kinase MET is frequently involved in malignant transformation and inhibiting its activity in MET-dependent cancers is associated with improved clinical outcomes. Emerging evidence also suggests that mitochondria play an essential role in tumorigenesis and Dynamin Related Protei...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Wang, Jiale, Mirzapoiazova, Tamara, Carol Tan, Yi-Hung, Pang, Ka Ming, Pozhitkov, Alex, Wang, Yingyu, Wang, Yang, Mambetsariev, Bolot, Wang, Edward, Nasser, Mohd W., Batra, Surinder K., Raz, Dan, Reckamp, Karen, Kulkarni, Prakash, Zheng, Yanfang, Salgia, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301806/
https://ncbi.nlm.nih.gov/pubmed/30311833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1472193
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