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PI3 Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma
Malignant pleural mesothelioma (MPM) is an aggressive cancer that is commonly associated with prior asbestos exposure. Receptor tyrosine kinases (RTKs) such as MET and its downstream target PI3K are overexpressed and activated in a majority of MPMs. Here, we studied the combinatorial therapeutic eff...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5021085/ https://ncbi.nlm.nih.gov/pubmed/27623107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32992 |
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