A novel co-existing ZCCHC8-ROS1 and de-novo MET amplification dual driver in advanced lung adenocarcinoma with a good response to crizotinib

In non-small cell lung cancer (NSCLC), driver gene alterations, such as EGFR, ALK, MET, and ROS1, are usually mutually exclusive. Few clinical cases with co-existing ROS1 fusion and de-novo MET amplification have been reported. In addition, the efficacy of crizotinib in Chinese patients with driver...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Zhu, You-cai, Wang, Wen-xian, Xu, Chun-wei, Zhuang, Wu, Song, Zheng-bo, Du, Kai-qi, Chen, Gang, Lv, Tang-feng, Song, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Bedside to Bench Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301800/
https://ncbi.nlm.nih.gov/pubmed/30095326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1491506
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