Regulation of gastric smooth muscle contraction via Ca(2+)-dependent and Ca(2+)-independent actin polymerization

In gastrointestinal smooth muscle, acetylcholine induced muscle contraction is biphasic, initial peak followed by sustained contraction. Contraction is regulated by phosphorylation of 20 kDa myosin light chain (MLC) at Ser(19), interaction of actin and myosin, and actin polymerization. The present s...

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Bibliographic Details
Published in:PLoS One
Main Authors: Mahavadi, Sunila, Nalli, Ancy D., Wang, Hongxia, Kendig, Derek M., Crowe, Molly S., Lyall, Vijay, Grider, John R., Murthy, Karnam S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301582/
https://ncbi.nlm.nih.gov/pubmed/30571746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209359
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