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Cytochrome P450 2E1 is responsible for the initiation of 1,2-dichloropropane-induced liver damage

1,2-Dichloropropane (1,2-DCP), a solvent, which is the main component of the cleaner used in the offset printing companies in Japan, is suspected to be the causative agent of bile duct cancer, which has been recently reported at high incidence in those offset printing workplaces. While there are som...

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Detalhes bibliográficos
Publicado no:Toxicol Ind Health
Main Authors: Yanagiba, Yukie, Suzuki, Tetsuya, Suda, Megumi, Hojo, Rieko, Gonzalez, Frank J, Nakajima, Tamie, Wang, Rui-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300984/
https://ncbi.nlm.nih.gov/pubmed/25681370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0748233714568801
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