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Cytochrome P450 2E1 is responsible for the initiation of 1,2-dichloropropane-induced liver damage

1,2-Dichloropropane (1,2-DCP), a solvent, which is the main component of the cleaner used in the offset printing companies in Japan, is suspected to be the causative agent of bile duct cancer, which has been recently reported at high incidence in those offset printing workplaces. While there are som...

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Publicado en:Toxicol Ind Health
Autores principales: Yanagiba, Yukie, Suzuki, Tetsuya, Suda, Megumi, Hojo, Rieko, Gonzalez, Frank J, Nakajima, Tamie, Wang, Rui-Sheng
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300984/
https://ncbi.nlm.nih.gov/pubmed/25681370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0748233714568801
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