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Enamine/Dienamine and Brønsted Acid Catalysis: Elusive Intermediates, Reaction Mechanisms, and Stereoinduction Modes Based on in Situ NMR Spectroscopy and Computational Studies

[Image: see text] Over the years, the field of enantioselective organocatalysis has seen unparalleled growth in the development of novel synthetic applications with respect to mechanistic investigations. Reaction optimization appeared to be rather empirical than rational. This offset between synthet...

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Veröffentlicht in:Acc Chem Res
Hauptverfasser: Renzi, Polyssena, Hioe, Johnny, Gschwind, Ruth M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2017
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300316/
https://ncbi.nlm.nih.gov/pubmed/29172479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.7b00320
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