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Enamine/Dienamine and Brønsted Acid Catalysis: Elusive Intermediates, Reaction Mechanisms, and Stereoinduction Modes Based on in Situ NMR Spectroscopy and Computational Studies

[Image: see text] Over the years, the field of enantioselective organocatalysis has seen unparalleled growth in the development of novel synthetic applications with respect to mechanistic investigations. Reaction optimization appeared to be rather empirical than rational. This offset between synthet...

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Detalhes bibliográficos
Publicado no:Acc Chem Res
Main Authors: Renzi, Polyssena, Hioe, Johnny, Gschwind, Ruth M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300316/
https://ncbi.nlm.nih.gov/pubmed/29172479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.7b00320
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