Design of Stapled Oxyntomodulin Analogs Containing Functionalized Biphenyl Cross-Linkers

A panel of three lipid-modified, functionalized biphenyl cross-linkers (fBph) were synthesized and subsequently employed in the preparation of the stapled oxyntomodulin (OXM) analogs. In a luciferase-based reporter assay, these stapled OXM analogs showed varying degree of potency in activating GLP-1...

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Detaylı Bibliyografya
Yayımlandı:Tetrahedron
Asıl Yazarlar: Tian, Yulin, Zou, Huafei, An, Peng, Zhou, Zhihong, Shen, Weijun, Lin, Qing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300064/
https://ncbi.nlm.nih.gov/pubmed/30581241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2018.11.060
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