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Mapping the landscape of tandem repeat variability by targeted long read single molecule sequencing in familial X-linked intellectual disability

BACKGROUND: The etiology of more than half of all patients with X-linked intellectual disability remains elusive, despite array-based comparative genomic hybridization, whole exome or genome sequencing. Since short read massive parallel sequencing approaches do not allow the detection of larger tand...

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Dettagli Bibliografici
Pubblicato in:BMC Med Genomics
Autori principali: Zablotskaya, Alena, Van Esch, Hilde, Verstrepen, Kevin J., Froyen, Guy, Vermeesch, Joris R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299999/
https://ncbi.nlm.nih.gov/pubmed/30567555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0446-7
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