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Hydrophilic azaspiroalkenes as robust bioorthogonal reporters
Two hydrophilic spiroalkenes, azaspiro[2.3]hex-1-ene and azaspiro[2.4]hept-1-ene, were designed and synthesized. Compared to the previously reported spiro[2.3]hex-1-ene, the azaspiroalkenes exhibited greater water solubility and reactivity as dipolarophiles in the photoindued tetrazale-alkene cycloa...
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| Publicado no: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6299827/ https://ncbi.nlm.nih.gov/pubmed/30483687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc07432a |
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