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A sterically shielded, stabilized nitrile imine for rapid bioorthogonal protein labeling in live cells
In pursuit of fast bioorthogonal reactions, reactive moieties have been increasingly employed for selective labeling of biomolecules in living systems, posing a challenge in attaining reactivity without sacrificing selectivity. To address this challenge, here we report a bioinspired strategy in whic...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5901669/ https://ncbi.nlm.nih.gov/pubmed/29565582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b00126 |
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