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Agonist redirected checkpoint, PD1-Fc-OX40L, for cancer immunotherapy
Simultaneous blockade of immune checkpoint molecules and co-stimulation of the TNF receptor superfamily (TNFRSF) is predicted to improve overall survival in human cancer. TNFRSF co-stimulation depends upon coordinated antigen recognition through the T cell receptor followed by homotrimerization of t...
Gardado en:
| Publicado en: | J Immunother Cancer |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6299665/ https://ncbi.nlm.nih.gov/pubmed/30563566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0454-3 |
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