Hyperpolarized [1-13C] pyruvate MR spectroscopy detect altered glycolysis in the brain of a cognitively impaired mouse model fed high-fat diet

Higher dietary intakes of saturated fatty acid increase the risk of developing Alzheimer’s disease and dementia, and even in people without diabetes higher glucose levels may be a risk factor for dementia. The mechanisms causing neuronal dysfunction and dementia by consuming high-fat diet degrading...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Choi, Young-Suk, Kang, Somang, Ko, Sang-Yoon, Lee, Saeram, Kim, Jae Young, Lee, Hansol, Song, Jae Eun, Kim, Dong-Hyun, Kim, Eosu, Kim, Chul Hoon, Saksida, Lisa, Song, Ho-Taek, Lee, Jong Eun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299662/
https://ncbi.nlm.nih.gov/pubmed/30563553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-018-0415-2
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