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An integrative approach for building personalized gene regulatory networks for precision medicine

Only a small fraction of patients respond to the drug prescribed to treat their disease, which means that most are at risk of unnecessary exposure to side effects through ineffective drugs. This inter-individual variation in drug response is driven by differences in gene interactions caused by each...

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Bibliographic Details
Published in:Genome Med
Main Authors: van der Wijst, Monique G. P., de Vries, Dylan H., Brugge, Harm, Westra, Harm-Jan, Franke, Lude
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299585/
https://ncbi.nlm.nih.gov/pubmed/30567569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0608-4
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