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Decoding Somatic Driver Gene Mutations and Affected Signaling Pathways in Human Medulloblastoma Subgroups

Medulloblastoma is the most common malignant pediatric brain tumor. Prior studies have concentrated their efforts studying the four molecular subgroups: SHH, Wnt, group 3, and group 4. SHH and Wnt are driven by their canonical pathways. Groups 3 and 4 are highly metastatic and associated with aberra...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Robbins, Charles J., Bou-Dargham, Mayassa J., Sanchez, Kevin, Rosen, Matthew C., Sang, Qing-Xiang Amy
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299398/
https://ncbi.nlm.nih.gov/pubmed/30588243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.27993
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