Decoding Somatic Driver Gene Mutations and Affected Signaling Pathways in Human Medulloblastoma Subgroups

Medulloblastoma is the most common malignant pediatric brain tumor. Prior studies have concentrated their efforts studying the four molecular subgroups: SHH, Wnt, group 3, and group 4. SHH and Wnt are driven by their canonical pathways. Groups 3 and 4 are highly metastatic and associated with aberra...

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Dettagli Bibliografici
Pubblicato in:J Cancer
Autori principali: Robbins, Charles J., Bou-Dargham, Mayassa J., Sanchez, Kevin, Rosen, Matthew C., Sang, Qing-Xiang Amy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299398/
https://ncbi.nlm.nih.gov/pubmed/30588243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.27993
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