The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex

Atrophic nonunion, a complicated failure of fracture healing, is still obscure regarding its molecular pathological mechanisms. Carboxyl-terminal binding proteins (CtBPs), an NADH-sensitive transcriptional corepressor family, are involved in many diseases, such as cancer and inflammation. Here, we f...

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Detalles Bibliográficos
Publicado en:Int J Biol Sci
Autores principales: Zhang, Wentao, Duan, Ning, Zhang, Qian, Song, Tao, Li, Zhong, Chen, Xun, Wang, Kunzheng
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2018
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299368/
https://ncbi.nlm.nih.gov/pubmed/30585266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.28302
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