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Gene code CD274/PD-L1: from molecular basis toward cancer immunotherapy

The programmed death 1 receptor (PD-1) and its ligand (PD-L1) are key molecules of immune checkpoint mechanisms in cancer and actually represent one of the main targets of immunotherapy. The predictive and prognostic values of PD-L1 expression alone in cancer patients is currently under debate due t...

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Detalhes bibliográficos
Publicado no:Ther Adv Med Oncol
Main Authors: Fabrizio, Federico Pio, Trombetta, Domenico, Rossi, Antonio, Sparaneo, Angelo, Castellana, Stefano, Muscarella, Lucia Anna
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299305/
https://ncbi.nlm.nih.gov/pubmed/30574211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835918815598
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