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Nrf2 and Notch Signaling in Lung Cancer: Near the Crossroad

The transcription factor Nrf2 (NF-E2 related factor 2) is a master regulator of the cell antioxidant response associated with tumor growth and resistance to cytotoxic treatments. In particular, Nrf2 induces upregulation of cytoprotective genes by interacting with the closely situated AREs (Antioxida...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Sparaneo, Angelo, Fabrizio, Federico Pio, Muscarella, Lucia Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099458/
https://ncbi.nlm.nih.gov/pubmed/27847554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7316492
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