Genetic polymorphisms of UGT1A1 and susceptibility to anti-tuberculosis drug-induced liver: A RUCAM-based case–control study

Uridine 5’-diphospho-glucuronosyl-transferase 1A1 (UGT1A1) plays an important role in the biliary excretion of bilirubin, suggesting genetic polymorphisms of UGT1A1 may have an impact on bile acid metabolism, which may be related to the development of anti-tuberculosis drug-induced liver injury (ATL...

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Detalhes bibliográficos
Publicado no:Int J Immunopathol Pharmacol
Main Authors: Tao, Bilin, Chen, Shixian, Lin, Guancheng, Yang, Miaomiao, Lu, Lihuan, He, Xiaomin, Pan, Hongqiu, Tang, Shaowen
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Letter to the Editor
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299304/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2058738418816288
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